CJC-1295 (No DAC)

Growth hormone axis Research compound (not approved for human use)

Growth hormone releasing hormone analog · also known as Mod GRF 1-29, Modified GRF (1-29)

For reference only — not medical advice. Figures are commonly reported values compiled from published sources and may be wrong or out of date. Many compounds listed are not approved for human use. Talk to a licensed clinician before using any compound.

CJC-1295 without DAC (also called Mod GRF 1-29) is a growth-hormone releasing hormone analog. The 'No DAC' version has a short duration, producing a short, pulsatile GH release, which is why it is frequently combined with a secretagogue like Ipamorelin.

Commonly reported dosing (5 mg vial)

Reconstituted with 3 mL → 1.667 mg/mL.

Also sold in 10 mg vials.

Phase	Dose	Volume	U-100 units
Starting Weeks 1-2	100 mcg	0.06 mL	6
Step Weeks 3-4	150 mcg	0.09 mL	9
Standard Weeks 5-6	200 mcg	0.12 mL	12
Higher Weeks 7-12 (250-300 mcg reported)	300 mcg	0.18 mL	18

Frequency: Once daily, commonly at bedtime (some reports use 1-3x daily), subcutaneous · Half-life: ~30 minutes (No DAC form)

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Commonly reported reconstitution steps

Vials are usually brought to room temperature (about 15-20 minutes) first.
3 mL of bacteriostatic water is added slowly down the inside wall of the 5 mg vial.
The vial is swirled gently until clear, not shaken.
This gives 1.67 mg/mL. Mixed vials are typically labeled with the date and refrigerated.

Storage

Before mixing: Sealed vials are commonly stored refrigerated (2-8 °C) and protected from light, or frozen for long-term storage.

After mixing: Reconstituted solution is commonly kept refrigerated (2-8 °C), protected from light, and not frozen.

Commonly used within 28 days of mixing.

How it works

CJC-1295 binds the GHRH receptor on the pituitary, amplifying the natural signal to release growth hormone. Without the DAC modification, the effect is brief and pulse-like.