Telus PeptidesEpitalon
Longevity Research compound (not approved for human use)
Synthetic tetrapeptide (Ala-Glu-Asp-Gly) · also known as Epithalon, Epitalone
For reference only — not medical advice. Figures are commonly reported values compiled from published sources and may be wrong or out of date. Many compounds listed are not approved for human use. Talk to a licensed clinician before using any compound.
Epitalon was designed by the St. Petersburg researcher Vladimir Khavinson as a synthetic version of the active tetrapeptide he reported in an extract of the pineal gland. It is among the most widely discussed so-called geroprotective peptides, with interest centered on telomere biology and circadian regulation.
Commonly reported dosing (10 mg vial)
| Phase | Dose | Volume | U-100 units |
|---|---|---|---|
| Standard | 5 mg | 1 mL | 100 |
Commonly reported reconstitution steps
- Vials are usually brought to room temperature (about 15-20 minutes) first.
- 2 mL of bacteriostatic water is added slowly down the inside wall of the 10 mg vial.
- The vial is swirled gently until clear, not shaken.
- This gives 5 mg/mL. Mixed vials are typically labeled with the date and refrigerated.
Storage
Before mixing: Lyophilized vials are commonly stored frozen (-20 °C).
After mixing: Reconstituted solution is commonly kept refrigerated (2-8 °C), protected from light, with freeze-thaw avoided.
How it works
Cell and animal studies report that Epitalon can raise telomerase expression and lengthen telomeres in some cell types, and it has been linked to melatonin rhythm and antioxidant effects. Independent replication in humans is limited.
Researched for
- Studied in human cell lines for telomerase induction and telomere elongation.
- Reported in animal models to extend lifespan and reduce tumor incidence in some strains.
- Examined in small, mostly Russian, human cohorts for age-related markers.
Notes
- Human data come largely from a single research group and are not independently confirmed.
- The 5 mg daily figure is the reference chart's standard; published regimens vary.
- A 10 mg vial reconstituted with 2 mL gives about 5 mg per mL.
Sources
Related
GHK-Cu
Copper-binding tripeptideGHK-Cu is a naturally occurring copper-binding tripeptide studied for skin, hair, and tissue-remodeling applications.
Pinealon
Synthetic tripeptide bioregulator (Glu-Asp-Arg)Pinealon is a three-residue peptide (glutamate, aspartate, arginine) developed by the Khavinson group as a brain-oriented bioregulator.
Vesugen
Synthetic tripeptide bioregulator (Lys-Glu-Asp)Vesugen is a three-residue peptide (lysine, glutamate, aspartate) from the Khavinson family, associated with blood vessels and the cardiovascular system.
Cartalax
Synthetic tripeptide bioregulator (Ala-Glu-Asp)Cartalax is a three-residue peptide (alanine, glutamate, aspartate) studied by the Khavinson group in connection with cartilage and connective tissue.
Livagen
Synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Ala)Livagen is a four-residue peptide (lysine, glutamate, aspartate, alanine) studied by the Khavinson group, with a liver-oriented label.
Testagen
Synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Gly)Testagen is a four-residue peptide (lysine, glutamate, aspartate, glycine) modeled on pituitary extracts, linked in the Khavinson literature to the pituitary-gonadal axis.