Testagen

Bioregulators Research compound (not approved for human use)

Synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Gly) · also known as KEDG, Lys-Glu-Asp-Gly

For reference only — not medical advice. Figures are commonly reported values compiled from published sources and may be wrong or out of date. Many compounds listed are not approved for human use. Talk to a licensed clinician before using any compound.

Testagen is tied in reviews to male reproductive system regulation, but direct evidence is thin. The most-cited animal work examined thyroid and thymus effects after pituitary removal in chickens, and no human trials exist.

Commonly reported dosing (20 mg vial)

Reconstituted with 3 mL → 6.667 mg/mL.

Phase	Dose	Volume	U-100 units
Starting Below about 2 units on a U-100 syringe at this concentration; not reliably measurable.	100 mcg	0.015 mL	1.5
Standard	200 mcg	0.03 mL	3
Higher	300 mcg	0.045 mL	4.5

Frequency: Once daily, subcutaneous (8-12 week courses, community-reported) · Half-life: Not well characterized in the published literature

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Commonly reported reconstitution steps

Vials are usually brought to room temperature (about 15-20 minutes) first.
3 mL of bacteriostatic water is added slowly down the inside wall of the 20 mg vial.
The vial is swirled gently until clear, not shaken.
This gives 6.67 mg/mL. Mixed vials are typically labeled with the date and refrigerated.

Storage

Before mixing: Lyophilized vials are commonly stored frozen (about -20 °C), dry, and protected from light.

After mixing: Reconstituted solution is commonly kept refrigerated (2-8 °C), protected from light, and freeze-thaw cycles are commonly avoided.

How it works

Hypothesized to interact with DNA and histones; in hypophysectomized birds a KEDG and AEDG pair reduced hormonal and structural changes in the thyroid.

Researched for

Studied in hypophysectomized chickens and old hens for thyroid hormone levels and gland structure.
Examined for effects on thymus morphology and immunity in similar bird models.
Described in reviews as a regulator of male reproductive function.

Notes

Despite the name, there is no published evidence that it raises testosterone in humans.
Evidence comes largely from a single research group (Khavinson and colleagues, St. Petersburg), mostly cell-culture and animal work; independent replication and controlled human trials are scarce.
Published human work from the originating group has mostly used oral or other non-vial formats; the vial, reconstitution and dosing figures here reflect community-reported conventions rather than trial-validated regimens.
Not FDA-approved.

Sources

Last reviewed 2026-10-06.

Prostamax

Synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Pro)

Prostamax is a four-residue peptide (lysine, glutamate, aspartate, proline) from the Khavinson family, associated with prostate tissue.

20 mg vial · Once daily, usually intramuscular with subcutaneous as an alternative (8-12 week courses, community-reported)

Livagen

Synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Ala)

Livagen is a four-residue peptide (lysine, glutamate, aspartate, alanine) studied by the Khavinson group, with a liver-oriented label.

20 mg vial · Once daily, subcutaneous (8-12 week courses, community-reported)

Vesugen

Synthetic tripeptide bioregulator (Lys-Glu-Asp)

Vesugen is a three-residue peptide (lysine, glutamate, aspartate) from the Khavinson family, associated with blood vessels and the cardiovascular system.

20 mg vial · Once daily, subcutaneous (8-12 week courses, community-reported)