Ovagen

Commonly reported reconstitution steps

1. Vials are usually brought to room temperature (about 15-20 minutes) first.
2. 2 mL of bacteriostatic water is added slowly down the inside wall of the 20 mg vial.
3. The vial is swirled gently until clear, not shaken.
4. This gives 10 mg/mL. Mixed vials are typically labeled with the date and refrigerated.

Storage

Before mixing: Lyophilized vials are commonly stored frozen (about -20 °C), dry, and protected from light.

After mixing: Reconstituted solution is commonly kept refrigerated (2-8 °C), protected from light, and freeze-thaw cycles are commonly avoided.

Researched for

• Studied in young and aged renal cell cultures for proliferation and senescence markers.
• Described in reviews as a renal-cell and hepatoprotective bioregulator.

Notes

• Unlike the other 3 mL entries, the reference lists 2 mL of diluent, giving about 10 mg/mL; the early amounts (10-20 mcg) correspond to 0.001-0.002 mL, below what a standard U-100 syringe can reliably resolve.
• Evidence comes largely from a single research group (Khavinson and colleagues, St. Petersburg), mostly cell-culture and animal work; independent replication and controlled human trials are scarce.
• Published human work from the originating group has mostly used oral or other non-vial formats; the vial, reconstitution and dosing figures here reflect community-reported conventions rather than trial-validated regimens.
• Not FDA-approved.